Artificial Intelligence in Complex Liver Cancer Surgery: Precision Oncological Resection

Technology Innovation /

Artificial intelligence (AI) is transforming complex liver cancer surgery by improving precision and patient outcomes. In preoperative planning, AI creates detailed 3D liver models from CT or MRI scans, accurately mapping tumors, blood vessels, and bile ducts. Surgeons can perform “virtual hepatectomies” to simulate resections, calculate remaining healthy liver tissue, and reduce postoperative liver failure […]

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Artificial Intelligence in Precision Oncology: Clinical Applications and Patient Outcomes

Precision Medicine /

Artificial intelligence (AI) is revolutionizing precision oncology by analyzing large datasets to guide personalized cancer care. It improves diagnosis, treatment selection, drug development, and risk assessment, leading to better patient outcomes. In diagnostics, AI rapidly interprets medical images and digital pathology slides, detecting subtle patterns and classifying cancer subtypes with high accuracy. It also predicts

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CAR-T Cell Therapy: Reprogramming the Immune System to Fight Cancer

Immunotherapy /

CAR-T cell therapy is a personalized immunotherapy that reprograms a patient’s T-cells to recognize and attack cancer. It has transformed treatment for certain blood cancers, providing hope for long-term remission in patients who have not responded to other therapies. The process begins with T-cell collection from the patient’s blood, followed by genetic modification in the

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Clinical trials for bladder cancer

Clinical Trails /

Clinical trials are exploring a range of innovative therapies for bladder cancer, aiming to improve outcomes while preserving the bladder. Intravesical and Targeted Therapies: Oncolytic viruses like cretostimogene grenadenorepvec and EG-70 are designed to selectively kill cancer cells and activate the immune system. Novel drug delivery systems, such as TAR-210, release chemotherapy (e.g., erdafitinib) over time

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RNA-Based Cancer Vaccines: Current Progress and Future Perspectives

Immunotherapy /

RNA-based cancer vaccines are rapidly advancing, showing real clinical impact across multiple cancer types. Personalized mRNA vaccines for melanoma, combined with pembrolizumab, reduced recurrence or death risk by 44% compared to pembrolizumab alone. In pancreatic cancer, mRNA vaccines generated long-lasting T-cell responses in half of patients, persisting up to four years. At the University of

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Expanding Treatment Arsenal: New Approvals for Gastrointestinal and Genitourinary Cancers

Treatment /

Recent approvals in gastrointestinal and genitourinary cancers are expanding treatment options with more precise and effective therapies. Pembrolizumab (Keytruda), a PD-1 checkpoint inhibitor, is now approved for colorectal, gastric, and esophageal cancers, showing durable responses, improved survival, and better quality of life for biomarker-selected patients. Trastuzumab (Herceptin), targeting HER2, benefits patients with HER2-positive gastric and

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FOTIVDA (Tivozanib): A Novel VEGFR Tyrosine Kinase Inhibitor for Advanced Renal Cell Carcinoma

Drug Approvals /

FOTIVDA (tivozanib) is an oral targeted therapy for adults with advanced renal cell carcinoma who have not responded to two or more prior systemic treatments. As a VEGFR tyrosine kinase inhibitor, it blocks VEGFR-1, -2, and -3, disrupting angiogenesis and depriving tumors of the blood supply needed for growth and progression. Treatment is given once

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Gene therapy for cancer treatment: past, present and future

Precision Medicine /

Gene therapy has become a promising cancer treatment by using the body’s genetic machinery to fight tumors, marking a major advance in personalized medicine. Initially, gene therapy in the late 20th century focused on delivering therapeutic genes via viral vectors, replacing defective tumor-suppressor genes like p53 or introducing “suicide genes” to make cancer cells drug-sensitive.

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Innovative treatment options for colorectal cancer

Technology Innovation /

Immunotherapy Checkpoint Inhibitors: Block proteins preventing immune system cancer attack, particularly effective for specific genetic features: MSI-H and dMMR Tumors: High mutation burden makes them immune-visible. Approved treatments include pembrolizumab (Keytruda), nivolumab (Opdivo), and nivolumab plus ipilimumab (Yervoy) for advanced colorectal cancer. The combination significantly improves progression-free survival versus single agents. Adoptive Cell Therapy: Extracts patient immune cells,

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Innovative Treatment Techniques in Cancer: A Glimpse into the Future of Oncology

Technology Innovation /

Immunotherapy and Cell-Based Therapies: 1. CAR-T Cell Therapy: Genetically modifies patients’ T-cells to recognize and attack specific cancer cells, then reinfuses them. Shows remarkable success in blood cancers like leukemia, lymphoma, and multiple myeloma. 2. Personalized Cancer Vaccines: Use mRNA technology (similar to COVID-19 vaccines) to create custom vaccines targeting individual tumor proteins, helping the immune system

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