preclinical trails

Researchers have developed a new three-drug treatment that completely eliminated pancreatic tumors in mice and stopped them from coming back. This is a major advance for pancreatic cancer, a disease with a five-year survival rate of about 13%. The therapy works by blocking three critical pathways that pancreatic tumors use to survive and grow. It […]

Researchers have created a nanoparticle “super vaccine” that prevented tumor formation in up to 88% of mice. Unlike traditional vaccines that use a single signal to alert the immune system, this new approach mimics a real infection, triggering a strong, body-wide immune response. The key is the lipid nanoparticle delivery system, which carries two immune-activating

The global obesity epidemic poses a major cancer risk, with over half of the world projected to be overweight or obese by 2035. Obesity increases the risk of at least 13 cancers, including breast and colorectal cancer, through metabolic, hormonal, and inflammatory mechanisms. The MeDOC consortium uses mouse models to study how obesity drives cancer