Research Advances

Researchers have developed a new two-step treatment strategy that targets mutations in the TP53 gene, a defect present in more than half of all cancers. Unlike older approaches that often cause significant toxicity, this method is designed to specifically attack cancer cells while leaving healthy cells largely unharmed. The treatment works in two stages. First, […]

GLP-1 receptor agonists, commonly used for diabetes and weight loss, may help reduce the risk of colorectal cancer. Drugs like semaglutide and tirzepatide showed promising results in a 2026 study, appearing more effective and safer than aspirin for prevention. People taking these drugs were 36% less likely to develop colorectal cancer, with risk reduced by

A study found that changes in gut bacteria and their metabolites may play an important role in rectal adenocarcinoma (READ). Researchers compared stool samples from 33 patients with rectal cancer and 34 healthy individuals and identified major differences in gut microbiota and metabolic activity. One key finding was that guanidinoacetic acid (GAA), a metabolite involved

A study shows that increasing daily steps can reduce the health risks of prolonged sitting. Using data from more than 72,000 participants in the UK Biobank, researchers tracked activity and health outcomes over nearly seven years. They found the greatest benefits at 9,000–10,000 steps per day, lowering the risk of death by 39% and cardiovascular

Researchers have identified a protein called HOXD13 as a key driver of melanoma. The study shows that HOXD13 helps cancer grow in two major ways. First, it promotes tumor growth by triggering angiogenesis, the process of forming new blood vessels. These vessels supply the tumor with oxygen and nutrients, allowing it to expand more quickly.

A study examined relapse in patients with myelofibrosis and blast-phase myeloproliferative neoplasms after allogeneic stem cell transplant. Among 47 patients treated between 2013 and 2024, 21% experienced recurrence, with 3- and 5-year relapse rates both at 35%. Molecular relapse typically appeared about six months after transplant and was often detected by declining donor chimerism. Donor

A new study has found a surprising link between healthy diets and a higher risk of lung cancer in non-smokers under age 50, especially women. Researchers reported that younger non-smokers diagnosed with lung cancer had better diet quality than average, scoring 65 on the Healthy Eating Index compared to the national average of 57. Women in

A natural compound extracted from purple sweet potatoes may offer a new way to fight colorectal cancer, according to a recent study. The compound, called Cya-Gly-Fer (CGF), showed strong anti-tumor effects in both laboratory and animal models, significantly slowing tumor growth and reducing liver metastasis, a major cause of death in colorectal cancer patients. Researchers

Researchers have developed a new nanomedicine, SH-EM-NP/EPI, aimed at improving treatment for bladder cancer by addressing key limitations of current therapies. In non-muscle-invasive bladder cancer (NMIBC), which accounts for about 75% of cases, recurrence rates remain high—up to 70% within five years—largely because drugs are quickly flushed out of the bladder and struggle to penetrate

A new study has developed the PNI-HB score, a simple blood-based tool to predict outcomes in patients with relapsed or refractory non-Hodgkin lymphoma undergoing CD19 CAR T-cell therapy. Unlike the traditional International Prognostic Index (IPI), the new model focuses on nutritional status and hemoglobin levels, offering a more relevant approach in the immunotherapy era. In