A new report from cancer research organizations highlights that 40% of all U.S. cancers are linked to modifiable risk factors, emphasizing prevention as a key strategy. Tobacco remains the largest contributor, causing nearly 20% of cancers and 17 different cancer types. Even e-cigarettes carry risks, increasing the likelihood of switching to traditional smoking. Maintaining a healthy weight, diet, and regular physical activity can prevent thousands of cases each year, as obesity accounts for 7.6% of cancers and poor diet for over 4%.
Alcohol and UV exposure are also significant contributors. Alcohol is linked to six cancer types, while UV radiation causes 95% of melanomas. Infection-related cancers, such as those from HPV, hepatitis B and C, and H. pylori, represent about 3.4% of cases, with vaccination rates for HPV still suboptimal. Environmental exposures, including air pollution, radon, and occupational hazards, further increase risk, with climate change intensifying some threats.
Hormonal factors like pregnancy timing, breastfeeding, and hormone therapy affect breast cancer risk. Early-onset cancers are rising due to lifestyle factors established in childhood, highlighting the need for prevention programs that ensure access to healthy food, safe spaces for exercise, and quality healthcare.