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Researchers have identified a new way to overcome chemotherapy resistance by targeting a protein called p300. Their study, published in Genes & Development, shows that blocking p300 pushes cancer cells into a fatal state of internal stress. Normally, when chemotherapy damages a cell’s DNA, p300 helps pause the cell’s activity so the damage can be […]

Researchers have discovered how the body’s own immune system can unintentionally help cancer grow. Neutrophils are white blood cells that normally fight infection. But the study shows that tumors can “reprogram” these cells. Instead of attacking cancer, the altered neutrophils begin producing a molecule called CCL3. This molecule acts like a growth signal, helping tumors

Researchers have found that where cancer spreads in the body may be decided by the tumor’s genes long before metastasis happens. Studying uveal melanoma, a rare eye cancer, they discovered a genetic reason why certain cancers tend to spread to specific organs. Although cancer cells can travel throughout the body, they only grow well in

New research highlights the complex role of the EI24 gene in cancer, showing that it can act either as a tumor suppressor or, in some cases, support tumor growth. EI24 is activated by the p53 tumor suppressor when DNA is damaged and plays a key role in autophagy and programmed cell death—two processes that help