July 13, 2026

Dostarlimab Continues to Show Strong Results in Locally Advanced Rectal Cancer

Treatment /

The phase 2 AZUR-1 trial has met its main goal, showing that dostarlimab (Jemperli) alone can produce a lasting complete response in patients with stage II/III dMMR/MSI-H locally advanced rectal cancer. An interim analysis found that many patients had no detectable signs of cancer 12 months or longer after starting treatment. The results suggest that […]

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Researchers Discover New Pathway That Fuels Cancer Growth

Research Advances /

Researchers have identified a new metabolic pathway that helps cancer cells grow and spread. The study, published in Nature Communications, reveals how changes in cell metabolism can directly activate genes that drive tumor progression. The team found that under stress, two mitochondrial enzymes, ACO2 and IDH2, move into the cell nucleus and produce acetyl CoA.

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