July 8, 2026

Study Identifies Protective Role of IgG Antibodies in Pancreatic Cancer

Research Advances /

A new study suggests that circulating IgG antibodies may help slow the growth and spread of pancreatic ductal adenocarcinoma (PDAC) by maintaining the tumor’s surrounding tissue and supporting anti-cancer immune responses. Using genetically engineered mouse models, researchers found that mice lacking circulating antibodies developed pancreatic tumors twice as fast and survived only about half as […]

Study Identifies Protective Role of IgG Antibodies in Pancreatic Cancer Read More »

Oral CDK2 Inhibitor Shows Promise in Platinum-Resistant Ovarian Cancer

Treatment /

The oral drug INCB123667 showed encouraging early results in patients with platinum-resistant ovarian cancer whose tumors overexpress cyclin E1, a protein linked to poor outcomes. In a Phase 1 trial, 14 patients receiving a 100-mg daily dose achieved an overall response rate of 35.7%, with all responses being partial. The disease control rate was 71.4%,

Oral CDK2 Inhibitor Shows Promise in Platinum-Resistant Ovarian Cancer Read More »

ctDNA Blood Test Helps Guide Chemotherapy After Colorectal Liver Metastasis Surgery

Treatment /

Updated results from the CIRCULATE-Japan GALAXY study show that a blood test for circulating tumor DNA (ctDNA) can help identify which patients benefit from chemotherapy after surgery for colorectal cancer liver metastases. Among patients who had surgery first, those with detectable ctDNA after surgery gained major benefits from adjuvant chemotherapy. Their four-year overall survival rate

ctDNA Blood Test Helps Guide Chemotherapy After Colorectal Liver Metastasis Surgery Read More »